Understanding Systemic Lupus Erythematosus (Lupus)

Systemic lupus erythematosus is a disease that causes your body's immune system to attack its own cells and tissues. It can affect your joints and nervous system. It can affect blood vessels. And it can affect organs such as the skin, kidneys, lungs, and brain. It can cause rashes, fatigue, pain, and fever. Severe lupus can cause harm to organs and other serious problems, including death.